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. Author manuscript; available in PMC: 2019 Jul 10.
Published in final edited form as: J Am Coll Cardiol. 2018 Jul 10;72(2):156–169. doi: 10.1016/j.jacc.2018.04.050

Table 5. Associations between rs7412 (reference/alternative alleles: C/T, MAF=0.08 in European Americans, MAF=0.11 in African Americans) and lipids.

Trait Meta-Analysis European Americans African Americans
Beta SE p Beta SE p Beta SE p
Log RLPC 0.267 0.02 2.64×10-32 0.264 0.027 6.01×10-23 0.275 0.042 6.10×10-11
Log TG 0.062 0.01 3.27×10-09 0.080 0.01 3.88×10-10 0.025 0.018 0.177279
HDL-C 1.170 0.32 0.0003 0.827 0.38 0.0273 2.193 0.647 7.07×10-4
HDL-2 0.044 0.01 0.0003 0.032 0.02 0.00901 0.070 0.022 9.00×10-05
HDL-3 0.463 0.22 0.0337 0.315 0.25 0.2113 0.909 0.436 0.0372
Log LDL-TG -0.139 0.01 5.68×10-39 -0.138 0.012 3.39×10-30 -0.140 0.022 2.35×10-10
LDL-C -16.581 0.817 1.20×10-91 -16.170 0.94 5.78×10-66 -17.815 1.64 1.22×10-27
TC -0.327 0.02 5.39×10-49 -0.304 0.03 3.22×10-32 -0.393 0.04 4.07×10-19
Non-HDL-C -0.358 0.02 1.83×10-52 -0.326 0.03 1.22×10-32 -0.447 0.05 1.15×10-22
Lp(a) -0.139 0.03 3.40×10-10 -0.12 0.03 3.66×10-05 -0.165 0.03 1.32×10-06