Fig. S2.

Reproducibility of the rich-club organization in L-AAL network. (A) Hub distribution of structural backbone network across all subjects. Network hubs are represented with nodes in red, with nodal size indicating the degree of the regions. (B) Mean normalized RC coefficient curve under a series of thresholds k for each group. (C) Group differences in the strength of the rich-club, feeder and local connections. The bars and error bars represent the mean values and standard deviations of the connection strength in each group after removing the effects of age and gender. *: p < 0.05; **: p < 0.01; ***: p < 0.005.