Table 1.
The demographic information and clinical characteristics of all participants.
| Controls (n = 35) |
CIS (n = 41) |
MS (n = 32) |
F/T/χ2/Z value | P value | |
|---|---|---|---|---|---|
| Age (years) | 35.0 ± 11.5 | 35.7 ± 10.7 | 34.8 ± 8.3 | 0.08a | 0.92a |
| Gender (F/M) | 23/12 | 26/15 | 24/8 | 1.17c | 0.56c |
| MMSE | 29.1 ± 1.3 | 27.6 ± 1.4 | 25.9 ± 1.8 | 36.44a | <0.001a |
| PASAT2 | 46.7 ± 9.2 | 39.4 ± 7.7 | 35.4 ± 9.8 | 14.14a | <0.001a |
| PASAT3 | 53.9 ± 6.2 | 47.5 ± 7.6 | 41.0 ± 8.7 | 24.38a | <0.001a |
| Disease duration (months) | – | 2.6 ± 2.5 | 41.8 ± 28.7 | 8.73b | <0.001b |
| TWMLL (ml) | – | 4.5 ± 10.6 | 10.3 ± 10.4 | 2.33b | 0.023b |
| EDSS (range) | – | 2.0 (0–6) | 3.5 (0–6.5) | 3.35d | <0.001d |
CIS, clinically isolated syndrome; MS, multiple sclerosis; MMSE = Mini-Mental State Examination; PASAT = Paced Auditory Serial Attention Test; EDSS = Expanded Disability Status Scale; TWMLL = Total White Matter Lesion Load.
Data are shown as mean ± standard deviation, except for EDSS presented in median (range).
a
P value and F value were obtained using one-way analysis of variance.
b
P value and T value were obtained using a two-sample t-test.
c
P value and χ2 value were obtained using the χ2 test.
d
P value and Z value were obtained using the Wilcoxon rank sum test.