Table 2. Haemodynamic variables at different time points.
| Variables | T1, Baseline | T2, pneumoperitoneum | T3, pneumoperitoneum + reverse-Trendelenburg | P value§ (ANOVA) |
|---|---|---|---|---|
| CO (L/min/m2) | 4.3±0.9 | 4.3±1.3 | 4.4±1.6 | 0.110 |
| MAP (mmHg) | 73±8 | 82±17 | 85±18 | 0.956 |
| CVP (mmHg) | 16±5 | 20±5* | 21±5* | <0.0001§ |
| SV (mL) | 67±9 | 66±23 | 66±27 | 0.980 |
| SVRI (dyne/sec/cm5) | 2,226±494 | 2,443±707 | 2,456±512 | 0.305 |
| SVV (%) | 9±3 | 13±7 | 19±10* | 0.005§ |
| MSFP (mmHg) | 22±4 | 25±5* | 27±6* | 0.001§ |
| PVR (mmHg) | 5.4±0.8 | 5.6±1.5 | 5.9±1.9 | 0.720 |
| Resistance-vr (mmHg/min/L) | 2.6±0.4 | 2.7±0.4 | 2.7±0.3 | 0.305 |
| MFI | 2.1±0.5 | 2.1±0.7 | 1.7±0.4* | 0.031§ |
| PVD (mm/mm2) | 24±11 | 22±11 | 24±10 | 0.573 |
Data are presented as mean ± SD. §, P value <0.05, the ANOVA is derived from the General Linear Model Repeated Measures of tests of within-subjects effects; *, P<0.05 versus T1 baseline. MAP, mean arterial pressure; CO, cardiac output; CVP, central venous pressure; SV, stroke volume; SVRI, systemic vascular resistance index; SVV, stroke volume variation; MSFP, mean systemic filling pressure; Resistance-vr, resistance of venous return; PVR, pressure gradient for venous return (Pmsa-CVP); MFI, microcirculatory flow index (for small vessels); PVD, perfused vessel density (for small vessels).