Table 3. Univariate and multivariate analysis of the risk factors for non-invasive ventilation failure.
| Variable | No. of patients with failures/total (%) | Univariate analysis | Multivariate analysis | AUC | |||||
|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | AUC | 95% CI | ||||
| BMI, kg/m2 | |||||||||
| <25 | 34/69 (49.3) | 1.00 | 1.00 | 0.642 | 0.538–0.745 | ||||
| ≥25 | 9/43 (20.9) | 0.27 | 0.11–0.65 | 0.21 | 0.07–0.65 | ||||
| Underlying disease | |||||||||
| None of the following | 26/49 (53.1) | 1.00 | |||||||
| Hypertension | 17/63 (27.0) | 0.33 | 0.15–0.72 | ||||||
| Etiology of respiratory failure | |||||||||
| None of the following | 25/85 (29.4) | 1.00 | 1.00 | 0.644 | 0.535–0.753 | ||||
| Pneumonia | 18/27 (66.7) | 4.80 | 1.90–12.12 | 6.40 | 2.08–19.71 | ||||
| Type of surgery | |||||||||
| None of the following | 38/87 (43.7) | 1.00 | |||||||
| Aorta surgery | 5/25 (20.0) | 0.32 | 0.11–0.94 | ||||||
| Blood transfusion | |||||||||
| No | 18/67 (26.9) | 1.00 | |||||||
| Yes | 25/45 (55.6) | 3.40 | 1.53–7.56 | ||||||
| Low cardiac output syndrome | |||||||||
| No | 22/77 (28.6) | 1.00 | |||||||
| Yes | 21/35 (60.0) | 3.68 | 1.59–8.52 | ||||||
| Renal failure before NIV | |||||||||
| No | 26/82 (31.7) | 1.00 | |||||||
| Yes | 17/29 (58.6) | 3.11 | 1.29–7.42 | ||||||
| Bilirubin, µmol/L | |||||||||
| <34 | 19/68 (27.9) | 1.00 | |||||||
| ≥34 | 24/44 (54.5) | 3.10 | 1.40–6.86 | ||||||
| PLT before NIV, ×109/L | |||||||||
| >130 | 5/32 (15.6) | 1.00 | |||||||
| ≤130 | 38/80 (47.5) | 4.80 | 1.71–13.97 | ||||||
| Vasoactive-inotropic score before NIV | |||||||||
| <6 | 11/53 (20.8) | 1.00 | 1.00 | 0.676 | 0.574–0.778 | ||||
| ≥6 | 32/59 (54.2) | 4.52 | 1.96–10.47 | 3.31 | 1.22–8.98 | ||||
| SOFA score before NIV | |||||||||
| <10.5 | 28/88 (31.8) | 1.00 | 1.00 | 0.666 | 0.557–0.774 | ||||
| ≥10.5 | 15/24 (62.5) | 7.56 | 2.69–21.25 | 6.81 | 2.06–22.46 | ||||
| Total | 0.830 | 0.752–0.907 | |||||||
AUC, area under the curve; BMI, body mass index; CI, confidence interval; NIV, non-invasive ventilation; OR, odds ratio; PLT, platelet count; SOFA, Sequential Organ Failure Assessment. Vasoactive-inotropic score: dosages of dopamine + dobutamine (ìg/kg/min) + [dosages of epinephrine + norepinephrine + isoproterenol (ìg/kg/min)] ×100 + dosages of milrinone (ìg/kg/min) ×15.