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. 2018 Jun;10(6):3849–3868. doi: 10.21037/jtd.2018.05.204

Table 7. Treatment schemes for Nocardia infection following lung transplantation.

Condition Initial scheme Alternative
Non-critical Trimethoprim-sulfamethoxazole 15 mg/kg in 3–4 daily doses Imipenem 500 mg 4 times daily or meropenem 1 g 3 times daily + amikacin 10–15 mg/kg once daily or minocycline 100 mg twice daily or linezolid 600 mg twice daily
Critical (disseminated, cerebral disease) Imipenem 500 mg 4 times daily or meropenem 1 g 3 times daily + amikacin 10–15 mg/kg once daily or trimethoprim-sulfamethoxazole 15 mg/kg in 3–4 daily doses Linezolid 600 mg twice daily or ceftriaxone 2 g twice daily or cefotaxime 2 g 3 times daily or minocycline 100 mg twice daily