Table 7. Treatment schemes for Nocardia infection following lung transplantation.
Condition | Initial scheme | Alternative |
---|---|---|
Non-critical | Trimethoprim-sulfamethoxazole 15 mg/kg in 3–4 daily doses | Imipenem 500 mg 4 times daily or meropenem 1 g 3 times daily + amikacin 10–15 mg/kg once daily or minocycline 100 mg twice daily or linezolid 600 mg twice daily |
Critical (disseminated, cerebral disease) | Imipenem 500 mg 4 times daily or meropenem 1 g 3 times daily + amikacin 10–15 mg/kg once daily or trimethoprim-sulfamethoxazole 15 mg/kg in 3–4 daily doses | Linezolid 600 mg twice daily or ceftriaxone 2 g twice daily or cefotaxime 2 g 3 times daily or minocycline 100 mg twice daily |