Table 3.
Characteristics | Unadjusted relative risk (95% confidence interval) | Adjusted relative risk (95% confidence interval) |
---|---|---|
BHLS score | 0.99 (0.78, 1.26) | 1.10 (0.84, 1.43) |
7 | 1.00 (0.86, 1.16) | 1.08 (0.92, 1.27) |
9 | 1.01 (0.91, 1.13) | 1.06 (0.96, 1.17) |
11 | Ref. | Ref. |
13.5 | ||
Age (years) | 1.94 (1.38, 2.72) | 1.77 (1.26, 2.47) |
20 | 1.39 (1.10, 1.76) | 1.33 (1.06, 1.67) |
30 | Ref. | Ref. |
40 | 0.70 (0.57, 0.85) | 0.65 (0.53, 0.80) |
50 | 0.48 (0.28, 0.81) | 0.39 (0.22, 0.68) |
60 | ||
Female sex (vs. male) | 1.01 (0.80, 1.29) | 0.67 (0.52, 0.88) |
Race/ethnicity | Ref. | Ref. |
White, non-Hispanic | 1.40 (1.11, 1.77) | 1.34 (1.06, 1.68) |
Black, non-Hispanic | 0.77 (0.37, 1.61) | 0.72 (0.37, 1.42) |
Hispanic | 0.70 (0.31, 1.54) | 0.74 (0.31, 1.74) |
Other/unknown | ||
Education (years)a | 0.91 (0.67, 1.24) | 0.95 (0.71, 1.27) |
8 | Ref. | Ref. |
12 | 0.97 (0.76, 1.24) | 1.06 (0.85, 1.33) |
14 | 0.85 (0.65, 1.11) | 1.01 (0.78, 1.31) |
16 | 0.62 (0.26, 1.46) | 0.86 (0.44, 1.69) |
20 | ||
HIV transmission risk factor | Ref. | Ref. |
MSM | 1.41 (1.02, 1.95) | 1.65 (1.19, 2.28) |
IDU | 1.34 (1.05, 1.73) | 1.46 (1.10, 1.94) |
Hetero | 1.66 (0.95, 2.92) | 1.93 (1.21, 3.08) |
Other/unknown | ||
Socioeconomic status | Ref. | Ref. |
Not low | 0.60 (0.37, 0.98) | 0.67 (0.42, 1.05) |
Low | 0.97 (0.82, 1.15) | 0.98 (0.82, 1.17) |
Very low | 1.85 (1.52, 2.25) | 1.80 (1.47, 2.19) |
Unknown | ||
Year of enrollment at VCCC | 0.98 (0.82, 1.16) | 0.84 (0.72, 0.99) |
2000 | Ref. | Ref. |
2003 | 0.96 (0.80, 1.14) | 1.01 (0.87, 1.18) |
2005 | 0.72 (0.51, 1.03) | 0.82 (0.58, 1.17) |
2010 | ||
Baseline CD4+ lymphocyte count (per 100 cells/mm3)a | 1.03 (1.00, 1.07) | 1.02 (0.98, 1.05) |
Baseline HIV-1 viral load (copies/mL)a | 1.02 (0.93, 1.11) | 0.97 (0.89, 1.07) |
Bold estimates are statistically significant (p < 0.05). BHLS score, age, education, and year of enrollment were continuous variables modeled using restricted cubic splines with four knots. As these numbers comprised < 5% of the total study sample, missing data were not imputed in the adjusted model, as they were not seen to be a source of significant bias
MSM men who have sex with men, IDU injection drug use, Hetero heterosexual contact
Some individuals were missing data: N = 16 individuals had missing education data, N = 1 individual had missing CD4+ lymphocyte count, and N = 1 individual had missing HIV-1 viral load