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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Neurobiol Dis. 2018 Jun 1;117:170–180. doi: 10.1016/j.nbd.2018.05.018

Figure 2. Nicotine treatment improves cognitive defects in Y-maze spontaneous alternation test at 7 months of age.

Figure 2

One-sample t test on percent alternations compared to chance level of zero was performed. Thy1-aSyn mice treated with vehicle showed decreased percentage of alternations at 7 months, but not at 5 months. Nicotine treatment at 0.4 mg/kg/h for 5 months (7 months of age) reversed the deficit. Data are represented as the mean ± SEM. ♦p<0.05, ∆not significant vs. chance level zero compared by one sample t test. A paired t test was also used to compare each group at 5 vs 7 months. ^p<0.05 compared to respective group at previous age.