Figure 3. CCI Suppresses Hippocampal Neurogenesis Late After Injury Independently of Ketamine.
(A) High resolution images of the GCL of the 4 treatment groups 6 weeks after injury. Dcx-expressing immature adult-born neurons are shown in white, with BrdU (red) and DAPI (blue). Scale bar = 25 μm. (B) CCI decreased the density of Dcx+ cells across treatment groups with no difference between ketamine and vehicle exposed groups. Bars represent mean cell densities (cells/mm3) and error bars represent SD; numbers inside bars represent the N for each group; *p < 0.05.