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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Neurobiol Dis. 2018 May 30;117:28–41. doi: 10.1016/j.nbd.2018.05.017

Figure 10. Cocaine induces increased cytoplasmic pMeCP2 and total MeCP2 and decreased nuclear pMECP2.

Figure 10

A) Graphic results from western analyses showing increased total MeCP2 in the cytoplasm of microglia after cocaine exposure. **p=002 via unpaired T-test. B) Graphic results from western analyses showing increased pMeCP2 in the cytoplasm (*p=0.0391 via unpaired T-test) and decreased nuclear pMeCP2 (**p=0.0299 via the unpaired T-test) of microglia after cocaine exposure. Results are expressed as mean ± SEM, n ≥ 3. C) Representative immunocytochemical labeling of control (untreated) and D) cocaine treated microglia with anti-MeCP2 (green) and Iba-1 (red) and DAPI (blue) showing cytoplasmic MeCP2. Magnification 40x, scale bar ~ 40um.