Table 2.
Comparison of Primary Outcomes between Intervention and Usual Care at Twelve Months
| Outcomes | HEPTIDES (n = 114) | Usual Care (n = 128) | p‐value | Adjusted Odds Ratio or Difference (95% Confidence Interval) |
|---|---|---|---|---|
| Depression severity | ||||
| Response—no/ total no (%) | 36/114 (31.6) | 19/128 (14.8) | .002 | 3.35 (1.71–6.53) |
| Remission—no/ total no (%) | 22/114 (19.3) | 9/128 (7.0) | .004 | 3.69 (1.56–8.74) |
| Depression‐free days, mean(SD)a | 118.7 (106.7) | 109.3 (117.9) | .53 | 30.70 (10.5–50.8) |
| HCV treatment | 11/114 (9.7) | 7/128 (5.5) | .22 | NA |
a
Intervention n = 109, usual care n = 123.
Only baseline covariates that predicted the outcomes in bivariate analyses (p < .20) were included in each multivariable regression model.
Response: age, race, cirrhosis status, baseline SCL‐20, depression treatment in the past 6 months, generalized anxiety disorder.
Remission: age, race, cirrhosis status, baseline SCL‐20, depression treatment in the past 6 months, generalized anxiety disorder.
Depression‐free days: age, race, cirrhosis status, baseline SCL‐20, depression treatment in the past 6 months, generalized anxiety disorder, panic disorder, post‐traumatic stress disorder.