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. 2018 Jul 18;8:10849. doi: 10.1038/s41598-018-29123-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of ATP level (a) and persister frequency (b) between S. aureus Newman wild type (WT) and atpA mutant. For ATP measurement (a) 3 different reads of luminescence signal were taken for each biological replicate. Persister frequency (b) was tested with 100 × MIC of ciprofloxacin and the samples for ATP measurement were taken after 24 hours of incubation right before the addition of ciprofloxacin. There were 3 biological replicates for each sample and error bars indicate standard deviation. Starting CFU/ml are indicated in Supplementary Table S2.