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. 2018 Jul 18;8:10862. doi: 10.1038/s41598-018-29190-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Known disease genes overlapping novel contigs. Overlap of non-dog genes aligning to contigs, genes associated with hereditary dog diseases (from OMIA), and genes associated with Mendelian human diseases (OMIM) in (a) Border Collies (b) Bearded Collies and (c) Entlebucher Sennenhunds. (d) There are 6 total genes represented in Border and Bearded Collie contigs that associate with diseases in humans and animal models. These genes are implicated in 54 human and 4 animal model disease phenotypes.