Table 1.
Symbola | Strain 1 | Strain 2 | Predicted shape changeb | Observed shape changec |
---|---|---|---|---|
Training | ||||
□ | ΔrodZ | WT | 0.109 | 0.101 |
□ | ΔrodZ + rodZ | WT | −0.022 | 0.000 |
∇ | ΔrodZ + rodZ59-337 | ΔrodZ + rodZ | 0.036 | 0.051 |
∇ | ΔrodZ + rodZ70-337 | ΔrodZ + rodZ | 0.082 | 0.076 |
∇ | ΔrodZ + rodZ83-337 | ΔrodZ + rodZ | 0.059 | 0.073 |
∆ | ΔrodZ + rodZ1-155 | ΔrodZ + rodZ | 0.012 | 0.005 |
∆ | ΔrodZ + rodZ1-142 | ΔrodZ + rodZ | 0.040 | 0.045 |
∆ | ΔrodZ + rodZ1-111 | ΔrodZ + rodZ | 0.077 | 0.070 |
□ | ΔrodZ + pTrc99A | WT | 0.071 | 0.098 |
∇ | ΔrodZ + rodZ59-337 | ΔrodZ + pTrc99A | −0.062 | −0.047 |
∇ | ΔrodZ + rodZ70-337 | ΔrodZ + pTrc99A | −0.016 | −0.022 |
∇ | ΔrodZ + rodZ83-337 | ΔrodZ + pTrc99A | −0.039 | −0.025 |
∆ | ΔrodZ + rodZ1-155 | ΔrodZ + pTrc99A | −0.086 | −0.093 |
∆ | ΔrodZ + rodZ1-142 | ΔrodZ + pTrc99A | −0.057 | −0.053 |
∆ | ΔrodZ + rodZ1-111 | ΔrodZ + pTrc99A | −0.020 | −0.028 |
□ | MreBS14A | WT | 0.020 | 0.013 |
□ | MreBE143A | WT | 0.017 | 0.007 |
□ | MreBY183N | WT | 0.075 | 0.120 |
□ | MreBS14A ΔrodZ | MreBS14A | 0.028 | 0.012 |
□ | MreBE143A ΔrodZ | MreBE143A | 0.072 | 0.053 |
Testing | ||||
• | MreBE143A ΔrodZ + pTrc99A | MreBE143A ΔrodZ + MreBE143A | 0.027 | 0.045 |
aSymbols used in Fig. 4 to show the different types of genetic perturbations included in the regression
bPredicted change in cell shape (ΔIDD = IDDstrain1 − IDDstrain2) is predicted from the regression model
cObserved change in cell shape is from 3D measurements of cells