Table 3.
Impact of demographic characteristics and OSA on EEG spectral activity in NREM sleep (first 6 h of sleep).
| SWA (μV2) | Theta activity (μV2) | Alpha activity (μV2) | Sigma activity (μV2) | |||||
|---|---|---|---|---|---|---|---|---|
| R | 0.654 | 0.483 | 0.322 | 0.344 | ||||
| r2 | 0.428 | 0.233 | 0.112 | 0.118 | ||||
| r2 adjusted | 0.392 | 0.184 | 0.055 | 0.062 | ||||
| p-value | <0.0001 | 0.0003 | 0.075 | 0.060 | ||||
| β (95% CI) | p–value | β (95% CI) | p-value | β (95% CI) | p-value | β (95% CI) | p-value | |
| Sex | 0.191 (0.103, 0.280) |
<0.0001 | 0.198 (0.087, 0.309) |
0.0006 | 0.116 (−0.013, 0.0.245) |
0.078 | 0.010 (−0.026, 0.224) |
0.119 |
| Age | −0.017 (−0.031, −0.002) |
0.024 | 0.004 (−0.014, 0.022) |
0.666 | −0.001 (−0.021, 0.021) |
0.981 | −0.012 (−0.032, 0.008) |
0.260 |
| LnBMI | 0.188 (−0.275, 0.652) |
0.422 | 0.122 (−0.462, 0.706) |
0.679 | 0.049 (−0.711, 0.757) |
0.888 | 0.014 (−0.643, 0.671) |
0.966 |
| Race/Ethnicity | −0.237 (−0.324, −0.149) |
<0.0001 | −0.208 (−0.318, −0.098) |
0.0003 | −0.166 (−0.294, −0.038) |
0.012 | −0.207 (−0.330, −0.083) |
0.001 |
| LnAHI | −0.057 (−0.126, 0.012) |
0.105 | −0.008 (−0.096, 0.079) |
0.851 | 0.018 (−0.084, 0.119) |
0.203 | 0.012 (−0.086, 0.110) |
0.816 |
| Sex x LnAHI | 0.001 | 0.066 | 0.119 | 0.798 | ||||
β coefficients and p-values from multiple regression models with spectral parameters as dependent variable and sex, age, LnBMI, race/ethnicity, LnAHI and sex x LnAHI interaction as covariates. The results of the statistical analysis reported were obtained after log-transformation of spectral frequency bands.
NREM, non-rapid eye movement sleep; SWA, slow-wave activity; BMI, body mass index; AHI, apnea-hypopnea index. Bold values indicate statistically significant p-values. Italic values indicate trends for statistical significance of p-value