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. 2018 Jul 18;8:10865. doi: 10.1038/s41598-018-28772-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The functions of extracted pigments from potatoes in H₂O₂-treated GES-1 cells. (A) The pigments isolated from potatoes were detected by HPLC. There were four significant peaks (i.e., Petunin, Paeonin, Malvidin and Pelargonidin) between 20 min and 26 min. (B) ARE-luciferase activity was examined in H₂O₂-treated GES-1 cells pre-incubated with the four pigments extracted from potatoes. Compared to the GES-1 and H₂O₂ groups, ARE-luciferase activity was elevated by the four extracted pigments. The highest ARE-luciferase activity was induced by Paeonin in H₂O₂-treated GES-1 cells; *P < 0.05, **P < 0.01 or ***P < 0.001 versus the H₂O₂ group.