Figure 7.

Physical model of CTT/pore interaction. A, geometry of the model showing the definitions of pore length l_p and tethering distance l_t. B, potentials corresponding to the escape of each CTT from the pore, calculated using optimized parameters l_t^α = 1.43 nm and l_t^β = 2.01 nm. Differences in escape times are described almost entirely by the heights of the barrier and not by residue-specific interactions between the CTT and the pore lumen.