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Inhibition activity of compounds 1–28 and 5-chloroisorotiorin against Influenza A Virus strains.
| Compounds | IC50 (μM)a | ||
|---|---|---|---|
| A/Puerto Rico/8/34 H274Y (H1N1) | A/FM-1/1/47 (H1N1) | A/Aichi/2/68 (H3N2) | |
| 14 | 21.80 ± 7.96 | 6.74 ± 1.26 | 6.17 ± 1.46 |
| 15 | 2.56 ± 0.32 | 4.82 ± 1.90 | 6.76 ± 2.72 |
| 26 | 9.40 ± 1.96 | 4.80 ± 1.28 | 5.12 ± 1.49 |
| 5-chloroisorotiorin | 2.52 ± 0.21 | 37.97 ± 15.11 | 10.10 ± 1.84 |
| Remainings | INb | IN | IN |
The samples were tested in triplicate, and the data are presented as the mean ± SD
Inactive.
