FIG 4.

Deletion of Cgmed3ab affects gene expression of cellular acetyl-CoA and pyruvate-related metabolism. Pyruvate dehydrogenase (PDH), ACS, and acetyl-CoA acyltransferase (pot1) are the main pathways in cellular acetyl-CoA biosynthesis, whereas acetyl-CoA carboxylase (ACC), citrate synthase (CS), and malate synthase (MS) are the main pathways in cellular acetyl-CoA biodegradation. Pyruvate kinase (PYK) and pyruvate decarboxylase (PDC) are the main pathways in pyruvate-related metabolism. TCA, tricarboxylic acid cycle. Each experiment was followed by three biological repeats; the error bars represent SD. *, P < 0.05; **, P < 0.01; ***, P < 0.001.