TABLE 1.

Kinetic thermostability and activity in organic solvents^a

Parameter	PaDa-I	Variant 16.5	Variant 6.1	Variant 7.1	Variant 4.7
Thermostability t1/2 (min)	8.7	43	16.6	2.9	8.7
C50 (%)
Acetonitrile	7.0	7.2	17.5	8.8	20.3
DMSO	2.0	1.7	2.8	1.3	2.3
Ethanol	1.0	1.0	1.0	1.0	1.0
Methanol	8.4	8.8	9.6	7.8	9.7
Acetone	10.0	11.6	13.2	8.1	13.1

^aValues were calculated from the t_1/2 and C₅₀ plots of Fig. S5 in the supplemental material.