TABLE 1.
Survival times of PLX5622-treated and untreated scrapie-infected C57BL/10 mice
| Treatment/strain (no. of mice in study group) | Survival times (dpi)a | Mean dpi ± SD |
|---|---|---|
| PLX5622/RML (14) | 115, 115, 117, 117, 117, 117, 126, 126, 133, 136, 136, 136, 142, 142 | 126.8 ± 10.5 |
| Untreated/RML (12) | 143, 153, 153, 153, 157, 157, 160, 160, 162, 163, 164, 164 | 157.4 ± 6.2 |
| PLX5622/ME7 (12) | 148, 150, 152, 152, 157, 157, 158, 158, 160, 161, 161, 161 | 156.3 ± 4.6 |
| Untreated/ME7 (12) | 166, 172, 172, 172, 174, 177, 177, 180, 180, 180, 180, 181 | 175.9 ± 4.7 |
| PLX5622/22L (9) | 126, 132, 132, 132, 133, 133, 133, 134, 135 | 132.2 ± 2.5 |
| Untreated/22L (10) | 139, 154, 154, 154, 155, 156, 156, 156, 162, 163 | 154.9 ± 13.0 |
a
Number of days postinfection when individual mice were euthanized due to the presence of advanced clinical signs.