Figure 1.

Aged‐associated increase of miR‐31a‐5p in BMSCs. (a) miR‐31a‐5p expression was increased in BMSCs from aged rats compared to that in the young (Y) and elderly rats (O) as analysed by qRT‐PCR, n = 5. (b) miR‐31a‐5p was detected at high levels in BMSCs from ovariectomized (OVX) rats versus BMSCs from sham rats, n = 5. (c) Significantly increased miR‐31a‐5p was observed in BMSCs at PDL‐15 versus BMSCs from early passages, n = 5. (d) Human BMSCs demonstrated that miR‐31a‐5p expression was increased with aging, n = 10. *p < 0.05, **p < 0.01. Data are presented as the mean ± SD