Table 3.
Comparison of baseline characteristics between survivors and non-survivors.
| Survivor (n = 128) | Non-survivor (n = 212) | p-value | |
|---|---|---|---|
| Age | 64 ± 14 | 69 ± 12 | .001 |
| Male, n (%) | 79 (40) | 135 (63) | NS |
| Sepsis status | |||
| Sepsis, n (%) | 5 | 5 | NS |
| Severe sepsis, n (%) | 40 | 49 | NS |
| Septic shock, n (%) | 71 | 170 | <.001 |
| Cause of sepsis | |||
| Thoracic, n (%) | 98 (48) | 107 (52) | NS |
| Intra-abdominal, n (%) | 21 (47) | 24 (53) | NS |
| Urogenital, n (%) | 14 (41) | 20 (59) | NS |
| Skin/soft tissue/bone, n (%) | 6 (55) | 5 (45) | NS |
| Other, n (%) | 11 (58) | 8 (42) | NS |
| Source unknown, n (%) | 11 (42) | 15 (58) | NS |
| Indication of CRRT | |||
| Oliguria, n (%) | 17 (46) | 20 (54) | NS |
| Hyperkalemia, n (%) | 4 (40) | 6 (60) | NS |
| Acidemia, n (%) | 13 (32) | 18 (68) | NS |
| Organ edema, n (%) | 16 (39) | 25 (61) | NS |
| Mixed, n (%) | 99 (45) | 122 (55) | NS |
| Comorbidity | |||
| Diabetes, n (%) | 63 (49) | 94 (44) | NS |
| Hypertension, n (%) | 90 (70) | 135 (64) | NS |
| Congestive heart failure, n (%) | 26 (21) | 51 (24) | NS |
| Liver cirrhosis, n (%) | 9 (7) | 38 (18) | .003 |
| Chronic kidney disease, n (%) | 47 (41) | 67 (59) | NS |
| Ischemic heart disease, n (%) | 37 (34) | 71 (66) | NS |
| Systolic blood pressure (mmHg) | 86 ± 25 | 79 ± 21 | .003 |
| Diastolic blood pressure (mmHg) | 52 ± 14 | 49 ± 13 | NS |
| APACHE 2 score | 24.5 ± 5.8 | 26.9 ± 5.7 | <.001 |
| SOFA score | 10.3 ± 3.1 | 12.5 ± 2.9 | <.001 |
| RBC transfusion | 2.7 ± 3.2 | 2.9 ± 4.6 | NS |
| Hemoglobin (mg/dl) | 10.3 ± 2.4 | 10.4 ± 2.4 | NS |
| Serum creatinine (mg/dl) | 4.2 ± 2.8 | 3.3 ± 2.7 | .007 |
| Total bilirubin (mg/dl) | 1.0 ± 1.4 | 2.7 ± 6.1 | .002 |
| Serum albumin (mg/dl) | 3.0 ± 0.7 | 2.8 ± 0.6 | .001 |
| WBC count (× 103/mL) | 15.3 ± 8.9 | 14.9 ± 9.2 | NS |
| C-reactive protein (mg/dl) | 11.6 ± 11.0 | 11.3 ± 11.2 | NS |
| RDW (%) | 14.9 ± 2.1 | 16.1 ± 3.3 | <.001 |
| Electrolyte | |||
| Na (mmol/L) | 136 ± 14 | 138 ± 6 | NS |
| K (mmol/L) | 4.5 ± 2.1 | 4.3 ± 0.9 | NS |
| Cl (mmol/L) | 101 ± 9 | 101 ± 7 | NS |
| Ca (mg/dl) | 7.8 ± 1.0 | 8.0 ± 0.9 | NS |
| P (mg/dl) | 5.1 ± 3.1 | 5.0 ± 2.5 | NS |
| Mg (mmol/L) | 2.4 ± 0.7 | 2.4 ± 0.6 | NS |
| ABGA | |||
| pH | 7.29 ± 0.14 | 7.27 ± 0.16 | NS |
| PaO2 (mmHg) | 97.7 ± 36.9 | 97.2 ± 56.2 | NS |
| PaCO2 (mmHg) | 32.2 ± 12.7 | 34.2 ± 13.1 | NS |
| HCO3 (mmol/L) | 14.2 ± 6.8 | 14.8 ± 6.8 | NS |
| Lactic acid levela (mmol/L) | 7.0 ± 7.6 | 7.9 ± 7.0 | NS |
| Platelet count (× 103/mL) | 178 ± 101 | 134 ± 84 | <.001 |
| UO <0.5 ml/kg/h during D1, n (%) | 84 (66) | 182 (86) | .001 |
APACHE: Acute Physiology and Chronic Health Evaluation; SOFA: sepsis-related organ failure; RBC: red blood cell; WBC: white blood cell; RDW: red blood cell distribution width; UO: urine output; ABGA: arterial blood gas analysis.
a
Lactic acid level was available in 255 patients.