Table 6.
Parameter | β (SE) | p-value | p-value (adjusted for BMI) |
---|---|---|---|
TC (mmol/L) | 0.168 (0.018) | 3.01 × 10−17 | 1.12 × 10−10 |
TG (mmol/L) | 0.090 (0.021) | 2.71 × 10−3 | 1 × 10−1 |
HDLC (mmol/L) | −0.498 (0.039) | 5.4 × 10−43 | 1.1 × 10−13 |
LDLC (mmol/L) | 0.211 (0.029) | 1.11 × 10−21 | 2.5 × 10−6 |
The beta effect means the rise or fall in the selected trait per each risk allele increase. For example, for TC, a beta effect of 0.168 means that with each risk allele increase, the serum total cholesterol increases by 0.168 mmol/L.