Table 3.
Anti-echovirus activity of M. barteri fractions and sub-fractions
| S/N | Fractions | CC50 (μg/mL) | IC50 (μg/mL) | SI | |||
|---|---|---|---|---|---|---|---|
| E7 | E13 | E19 | E7 | E19 | |||
| 1 | Hexane | 24.9 | 0.44 | NA | 0.31 | 57.96 | 83.85 |
| 2 | DCM | 0.18 | 7.54*10−6 | NA | 1.75*10−6 | 19,865.54 | 8581.24 |
| 3 | DCMA | 2.97 | 0.09 | NA | 0.54 | 33.82 | 5.50 |
| 4 | DCMB | 0.89 | 0.03 | NA | 0.05 | 28.21 | 16.38 |
| 5 | DCMC | 0.63 | NA | NA | 0.01 | – | 54.59 |
| 6 | DCMD | 1.31 | 4.80*10−3 | NA | 0.01 | 247.70 | 246.1 |
| 7 | DCME | 0.47 | 0.02 | NA | 0.01 | 24.23 | 44.09 |
| 8 | DCMF | 24.35 | 1.61 | NA | 1.82 | 15.13 | 13.36 |
| 9 | EtOAc | 2.87 | NA | NA | NA | – | NA |
| 10 | Aqueous | 3.061 | NA | NA | NA | – | NA |
NA Not Active, SI Selectivity Index