Table 4.
Levels of protein, LPO, GSH, vitamins-A, C, E and activities of SOD and GPx in saliva of control and OSF patients in different clinical stage based on fibrotic bands
| Parameters | Group | F value | R 2 | |||
|---|---|---|---|---|---|---|
| Control (n = 63) | Fibrotic bands | |||||
| Grade I (n = 20) | Grade II (n = 23) | Grade III (n = 20) | ||||
| Protein (mg/ml) | 2.27 ± 0.0.34 | 2.76 ± 0.52b | 2.70 ± 0.56b | 2.85 ± 0.74b | 6.78c | 0.343# |
| LPO (μM MDA/ml) | 15.86 ± 4.63 | 195.08 ± 70.77c | 210.97 ± 66.93c | 183.54 ± 54.64 | 168.65c | 0.763# |
| GSH (μM/ml) | 474.6 ± 47.2 | 478.02 ± 87.65NS | 471.65 ± 87.64NS | 442.81 ± 76.04NS | 1.26NS | −0.136NS |
| Vitamin A (µg/ml) | 379.20 ± 99.63 | 228.56 ± 26.17c | 235.06 ± 32.02c | 223.40 ± 48.52c | 41.45c | −0.625# |
| Vitamin E (µg/ml) | 558.47 ± 88.88 | 429.25 ± 83.64c | 427.08 ± 79.69c | 371.30 ± 110.71c | 30.14c | −0.441# |
| Vitamin C (µg/ml) | 302.65 ± 95.32 | 255.87 ± 92.22 | 229.96 ± 57.74c | 194.42 ± 71.76c | 9.93c | −0.658# |
| SOD (U/mg protein | 1.42 ± 0.28 | 0.79 ± 0.18c | 0.72 ± 0.21c | 0.64 ± 0.26c | 81.24c | −0.754# |
| GPx (mM of GSH reduced/min/mg protein) | 1.41 ± 0.38 | 1.01 ± 0.32c | 0.81 ± 0.28c | 0.75 ± 0.37c | 27.84c | −0.661# |
Values are expressed as Mean ± SD
Statistical comparison by Dunnett’s post hoc test are expressed as a p < 0.05; b p < 0.01; c p < 0.001; NS non-significant for comparisons: control versus grade I, grade II and grade III
For correlation analysis, as # p < 0.01; NS non-significant