Table 5.
Levels of protein, LPO, GSH, vitamins-A, C, E and activities of SOD and GPx in saliva of control and OSF patients in different histological grades
| Parameters | Group | F value | R 2 | ||||
|---|---|---|---|---|---|---|---|
| Control (n = 63) | Histological grade | ||||||
| Grade I (n = 3) | Grade II (n = 7) | Grade III (n = 4) | Grade IV (n = 49) | ||||
| Protein (mg/ml) | 2.27 ± 0.66 | 2.89 ± 0.16a | 2.47 ± 0.41NS | 2.77 ± 0.70NS | 2.80 ± 0.63c | 5.35c | 0.37# |
| LPO (μM MDA/ml) | 15.86 ± 4.63 | 185.94 ± 72.83c | 155.44 ± 40.20c | 228.64 ± 89.85c | 201.31 ± 64.02c | 131.35c | 0.869# |
| GSH (μM/ml) | 474.6 ± 47.2 | 481.95 ± 117.1NS | 419.2 ± 61.07 | 438.02 ± 132.93NS | 472.08 ± 81.05 | 1.31NS | −0.034NS |
| Vitamin A (µg/ml) | 379.20 ± 99.63 | 216.26 ± 15.01c | 241.14 ± 31.62c | 240.60 ± 29.11c | 227.47 ± 38.35c | 30.9c | −0.675# |
| Vitamin E (µg/ml) | 558.47 ± 88.88 | 480.00 ± 54.8NS | 373.85 ± 87.87b | 462.50 ± 90.3NS | 406.67 ± 95.45c | 21.97c | −0.425# |
| Vitamin C (µg/ml) | 302.65 ± −95.32 | 266.76 ± 89.92a | 276.72 ± 90.36NS | 217.38 ± 122.73NS | 218.13 ± 69.86c | 6.89c | −0.633# |
| SOD (U/mg protein | 1.42 ± 0.28 | 0.77 ± 0.23a | 0.64 ± 0.23b | 0.85 ± 0.20a | 0.71 ± 0.22c | 59.29c | −0.767# |
| GPx (mM of GSH reduced/min/mg protein) | 1.41 ± 0.38 | 1.15 ± 0.077b | 0.863 ± 0.269b | 1.04 ± 0.37a | 0.82 ± 0.345c | 19.85c | −0.614# |
Values are expressed as Mean ± SD
Statistical comparison by Dunnett’s post hoc test are expressed as a p < 0.05; b p < 0.01; c p < 0.001; NS non-significant for comparisons: control versus grade I, grade II, grade III and grade IV
For correlation analysis, as # p < 0.01 NS non-significant