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. Author manuscript; available in PMC: 2018 Jul 19.
Published in final edited form as: Pharmazie. 2009 Aug;64(8):525–531.

Table 5.

Plasma profile of Mean ± SD (n = 6) diltiazem concentration following administration of 15 mg/kg b wt p.o with water (control), single and multiple dose GFJ

Parameters units Diltiazem Single dose GFJ Multiple dose GFJ
Mean SD Mean SD Mean SD
Cmax ng/ml 120.78 16.36 92.82 (23.1%) 15.12 40.95 (66.09%) 23.96
AUC0–24 ng · hr/ml 43.63 8.16 43.08 (1.26%) 9.44 24.77 (43.22%) 18.18
AUC0–∞ ng · hr/ml 62.77 17.82 51.48 (17.98) 10.16 33.71 (35.14%) 9.31
Tmax hr 0.08 0 0.08 (0%) 0.07 0.43 (437.5%) 0.33
T1/2 hr 0.49 0.28 0.52 (6.12%) 0.08 1.16 (136.7%) 0.63

(n = 6) P < 0.05. The values mentioned in bracket are expressed as % inhibition compared to that of control