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. 2018 Jul 18;9:957. doi: 10.3389/fphys.2018.00957

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Copyright © 2018 Dharmaprani, Dykes, McGavigan, Kuklik, Pope and Ganesan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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AF detection using COSEn (Coefficient of sample entropy). CoSEn values for ECGs from the MIT-BIH atrial fibrillation database used by Lake and Moorman (2010) to test automated AF detection using SampEn. Although CoSEn was able to differentiate between normal sinus rhythm (A) and atrial fibrillation (B), sinus rhythm with ectopy (C), and atrial flutter (AFL) (D) resulted in misclassification. This was due to (i) irregular RR intervals for sinus with ectopy, which increased SampEn and mimicked AF values for CoSEn and (ii) 2:1 AFL creating regular RR intervals, mimicking sinus values for CoSEn. Reprinted from Lake and Moorman (2010) with permission.