Table 1.
Demographics and clinical tests including Unified Parkinson's Disease Rating Scale part III (UPDRS III), Montreal Cognitive Assessment (MoCA), REM sleep Behavior Disorder Questionnaire (RBDSQ), and University of Pennsylvania Smell Identification Test (UPSIT) scores at Baseline (BL) and after a year, visit 04 (V04) in Parkinson's disease (PD) and control subjects.
| PD (n = 112) | Control (n = 110) | P-value (PD, control) [two-sample t-test] | P-value (BL, V04) [paired sample t-test] | |
|---|---|---|---|---|
| Age (years) (mean ± SD) | 60.89 ± 10.46 | 61.54 ± 10.03 | 0.6381a | – |
| Gender (Male Number/ %) | 80 M/71.42% | 69 M/62.72% | 0.2465b | – |
| Disease duration (months) (mean ± SD) | 14.23 ± 14.08 | – | – | – |
| UPDRS III (BL) (mean ± SD) | 19.15 ± 8.16 | 2.41 ± 1.39 | 0.0000a | 0.0027c(PD) |
| UPDRS III (V04) (mean ± SD) | 22.98 ± 10.52 | 3.12 ± 1.92 | 0.0000a | 0.1555c(control) |
| MoCA (BL) (mean ± SD) | 27.03 ± 2.10 | 28.22 ± 1.06 | 0.0000a | 0.0031c(PD) |
| MoCA (V04) (mean ± SD) | 26.34 ± 2.42 | 27.29 ± 2.10 | 0.0023a | 0.0000c(control) |
| RBDSQ (BL) (mean ± SD) | 4.17 ± 2.89 | 3.95 ± 2.89 | 0.5358a | 0.3394c(PD) |
| RBDSQ (V04) (mean ± SD) | 3.99 ± 2.82 | 3.60 ± 2.99 | 0.6371a | 0.5694c(control) |
| UPSIT baseline (mean ± SD) | 20.77 ± 8.03 | 33.99 ± 4.69 | 0.0000a | – |
n, number; SD, standard deviation.
a
p-values obtained by independent samples t-test.
b
p-values obtained by chi-square independence test.
c
p-values obtained by paired samples t-test (difference between clinical scores at baseline and after 1-year follow-up).