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Effects of cholinergic differentiation with dibutyryl-cAMP/RA (DC) and/or with nerve growth factor (NGF) and amyloid-β (Aβ) on PDHC and ChAT activities, acetyl-CoA distribution, acetylcholine content and loss of viability of (A,B) cholinergic neuroblastoma SN56 with surface TrkA(+) and p75NTR(+) NGF receptors; (C,D) SN56 with TrkA(–) and p75NTR(+) NGF receptors. Absolute values of enzyme activities and metabolite levels corresponding to 0 ordinate are given in Table 3.
