Table 5.
Multivariable Logistic Regression for Prediction of Secondary Outcomes Renal Replacement Therapy Utilization#
| Model Terms | Odds Ratio of Either Renal Angina+ or SCr>Base for AKIS | |
|---|---|---|
| RA+ | SCr>Base | |
| Age > 83 months | 2.03 (0.61–6.69) | 2.47 (0.78–7.77) |
| BSA > 0.87 m2 | 0.50 (0.15–1.69) | 0.40 (0.13–1.31) |
| Shock Dx | 2.52 (1.24–5.13) | 3.02 (1.52–6.03) |
| Cardiovascular Dx | 1.25 (0.36–4.34) | 1.26 (0.37–4.32) |
| Absence of Trauma Dx | 2.56 (0.83–7.89) | 2.45 (0.80–7.47) |
| Absence of CNS Dx | 1.16 (0.46–2.90) | 1.19 (0.48–2.97) |
| Transplant Hx | 3.32 (1.34–8.19) | 4.22 (1.75–10.15) |
| Renal Angina | 4.12 (2.08–8.17) | n/a |
| SCr>Base | n/a | 1.92 (0.97–3.82) |
| Model Terms | Inclusion of both Renal Angina+ and SCr>Base into Regression Model | |
| Age > 83 months | 2.03 (0.61–6.68) | |
| BSA > 0.87 m2 | 0.50 (0.15–1.69) | |
| Shock Dx | 2.52 (1.24–5.13) | |
| Cardiovascular Dx | 1.25 (0.36–4.34) | |
| Absence of Trauma Dx | 2.56 (0.83–7.89) | |
| Absence of CNS Dx | 1.16 (0.46–2.90) | |
| Transplant Hx | 3.30 (1.33–8.21) | |
| SCr>Base | 1.02 (0.46–2.31) | |
| Renal Angina | 4.07 (1.83–9.04) | |
| Mortality^ | ||
| Model Terms | Exclusion of Either Renal Angina+ or SCr>Base from Regression Model | |
| RA+ | SCr>Base | |
| Shock Dx | 1.12 (0.66–1.89) | 1.29 (0.78–2.15) |
| Cardiovascular Dx | 2.59 (1.25–5.42) | 2.64 (1.27–5.47) |
| Absence of Trauma Dx | 2.09 (0.91–4.78) | 2.02 (0.88–4.61) |
| CNS Dx | 2.53 (1.48–4.31) | 2.42 (1.43–4.11) |
| Transplant History | 1.32 (0.59–2.95) | 1.52 (0.69–3.37) |
| Renal Angina | 2.38 (1.36–4.15) | n/a |
| SCr>Base | n/a | 1.22 (0.75–1.99) |
| All-stage AKI | 0.99 (0.59–1.68) | 1.15 |
| ECMO | 2.56 (0.80–8.16) | 2.55 (0.81–8.06) |
| RRT Use | 6.05 (2.89–12.63) | 7.48 (3.65–15.31) |
| Model Terms | Inclusion of both Renal Angina+ and SCr>Base into Regression Model | |
| Odds Ratio | 95% CI | |
| Shock Dx | 1.16 | 0.66–1.88 |
| Cardiovascular Dx | 2.59 | 1.24–5.43 |
| Absence of Trauma Dx | 2.11 | 0.92–4.83 |
| CNS Dx | 2.52 | 1.48–4.30 |
| Transplant Hx | 1.34 | 0.60–2.99 |
| SCr>Base | 0.86 | 0.49–1.51 |
| Renal Angina | 2.58 | 1.36–4.89 |
| All stage AKI | 1.01 | 0.60–1.71 |
| ECMO | 2.59 | 0.81–8.23 |
| RRT Use | 6.04 | 2.89–12.59 |
#
58 patients,
^
81 patients
Model terms included demonstrated bivariate association with outcome p ≤ 0.15
BSA = body surface area, Dx = diagnosis, Hx = history, CNS = central nervous system, SCr>Base = Serum creatinine greater than baseline creatinine, RA+ = renal angina fulfillment, AKI = acute kidney injury, ICU = intensive care unit, ECMO = extracorporeal membrane oxygenation, RRT=Renal replacement therapy