Table 1. Clinical and biochemical parameters for the healthy, WDM-NP, DM-WNP, and DM-NP subjects.
| Unit | Healthy (n = 50) |
WDM-NP (n = 48) |
DM-WNP (n = 87) |
DM-NP (n = 53) |
|
|---|---|---|---|---|---|
| Gender (M/F) | None | 23/27 | 19/29 | 47/40 | 27/26 |
| Age | years | 51.6 (7.6) | 64.3 (15.3) | 61.1 (11.0) | 65.5 (11.5) |
| BMI | kg/m2 | 23.5 (3.5) | 25.2 (5.3) | 25.0 (3.2) | 26.2 (4.0) |
| HbA1c | % | 5.5 (0.4) | 5.8 (0.4) | 6.6 (0.5) | 6.9 (0.6) |
| Creatinine | mg dL-1 | 1.0 (0.2) | 1.2 (1.4) | 0.80 (0.20) | 0.80 (0.20) |
| eGFR | ml/min | 76.0 (10.7) | 67.1 (28.0) | 92.8 (22.7) | 88.6 (24.0) |
| Albuminuria | mg dL-1 | 0.7 (0.5) | 534.6 (980.0) | 7.1(8.1) | 85.9(103.1) |
| Urine creatinine | mg dL-1 | 118.7(66.2) | 141.9 (228.9) | 90.3 (59.3) | 78.7 (53.3) |
| Urine ACR | mg/g | 6.3 (4.0) | 961.1 (1911.5) | 8.1 (6.9) | 106.1 (70.4) |
Values are expressed as the mean ± standard deviation. WDM-NP group, patients with micro- or macroalbuminuria due to nondiabetic disease; DM-WNP group, patients with diabetes mellitus (DM) without micro- or macroalbuminuria; DM-NP, patients with DM with microalbuminuria; BMI, body mass index; eGFR, estimated glomerular filtration rate; ACR, albumin-to-creatinine ratio.