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. 2018 Jul 19;13(7):e0200887. doi: 10.1371/journal.pone.0200887

Table 1. Contrast agent application protocols (group 1–4) for acquisition of gadoxetate disodium-enhanced MR images and characteristics of patients included in each group.

Protocol No. Injection rate Contrast dose BMI Nasal oxygen Number of patients Sex Age MRI indication
1 2 ml/sec 0.025 mmol/kg
(= 0.1ml/kg)
27 (16–42) no 50 male = 40
female = 10
mean 52y
(26-75y)
Cirrhosis (n = 12) PSC (n = 16) Tumor (n = 17) Other n = (5)
2 2 ml/sec fixed 10 ml 24 (16–35) no 50 male = 29
female = 21
mean 50y
(19-84y)
Cirrhosis (n = 10) PSC (n = 23) Tumor (n = 11) Other (n = 6)
3 1 ml/sec 0.025 mmol/kg
(= 0.1ml/kg)
27 (19–45) no 50 male = 30
female = 20
mean 50y
(19-73y)
Cirrhosis (n = 10) PSC (n = 11) Tumor (n = 20) Other (n = 9)
4 1ml /sec 0.025 mmol/kg
(= 0.1ml/kg)
26 (16–46) yes 50 male = 30
female = 20
mean 52y
(18-79y)
Cirrhosis (n = 11) PSC (n = 11) Tumor (n = 19) Other (n = 9)

BMI = body mass index (mean, range in brackets); PSC = primary sclerosing cholangitis