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. Author manuscript; available in PMC: 2019 Apr 15.
Published in final edited form as: Am J Cardiol. 2018 Feb 2;121(8):903–909. doi: 10.1016/j.amjcard.2017.12.038
Men
(N=807)
Women
(N=309)
Model 1 Model 2 Model 1 Model 2
Measure Hazard Ratio (95%CI) P Value C-Statistic Hazard Ratio (95%CI) P Value C-Statistic Hazard Ratio (95%CI) P Value C-Statistic Hazard Ratio (95%CI) P Value C-Statistic
Waist circumference sex-adjusted tertiles*
Low Referent Referent Referent Referent
Middle 1.27 (0.89,1.83) 0.50 1.24 (0.86,1.78) 0.61 1.57 (0.79, 3.15) 0.61 1.57 (0.78,3.17) 0.63
High 1.30 (0.91, 1.85) 0.25 1.21 (0.84, 1.73) 0.40 3.28 (1.75,6.36) 0.0008 3.42 (1.80, 6.74) 0.0006
0.50 0.61 0.61 0.62
Waist circumference continuous, for 1 cm increase 1.00 (0.99,1.01) 0.16 1.00 (0.99, 1.01) 0.26 1.02 (1.01,1.04) 0.0003 1.02 (1.01, 1.03) 0.0006

Cl= confidence interval

Model 1: Adjusted for age, Model 2: Adjusted for Age, smoking and history of heart failure. (The variable Waist circumference was available in less subjects than those included in table 3)

Interaction between Body mass index and waist circumference (in a model with Body mass index and waist circumference), was not statistically significant (p=>0.05).

*

Waist circumference sex-adjusted tertiles [Men Low: <98 cms (N=291 ,MACE=64), Middle: 98 cms to <108.56 cms (N=247, MACE=58), High: ≥108.56 cms (N=269, MACE=60); Women Low: 87 cms (N=106,MACE=19), Middle: 87 cms to <101 cms (N=100,MACE=18), High: ≥101 cms (N=103,MACE=29)j