Table 4. Gross and adjusted Hazard Ratio (HR) of the prognostic factors of death among patients who had suffered non-infectious adverse events in an intensive care unit of Rio Branco, Acre, Brasil, 2012-2014.
| Variable | Hazard Ratio gross (95% CI) | Hazard Ratio adjusted (95% CI)* | |
| Age | |||
| <50 years old | 1.00 | 1.00 | |
| 50 or more | 1.62 (1.05-2.49) | 1.57(1.01-2.43) | |
| Sex | |||
| Male | 1.00 | 1.00 | |
| Female | 0.77 (0.51-1.17) | 0.84 (0.55-1.29) | |
| Hospitalization | |||
| Clinical | 1.00 | 1.00 | |
| Surgical | 1.57 (0.99-2.48) | 1.42 (0.89-2.27) | |
| Reason for hospitalization | |||
| Trauma | 1.00 | 1.00 | |
| Cardiovascular disorders | 2.20 (0.85-5.70) | 1.76 (0.65-4.77) | |
| Infection/sepsis | 3.07 (1.43-6.59) | 2.62 (1.18-5.78) | |
| Neurological disorders | 2.03 (0.97-4.27) | 1.72 (0.79-3.75) | |
| Other clinical changes | 1.73 (0.80-3.75) | 1.41 (0.62-3.20) | |
| Surgery | 1.45 (0.70-3.02) | 1.32 (0.63-2.78) | |
| AE† per patients‡ | |||
| 01 AE† | 1.00 | 1.00 | |
| 02 AE† | 0.45 (0.25-0.77) | 0.52 (0.29-0.93) | |
| 03 or more AE† | 0.23 (0.13-0.43) | 0.22 (0.11-0.41) | |
| SAPS3§ | |||
| ≤30 | 1.00 | 1.00 | |
| 31-60 | 2.19 (1.34-3.60) | 2.12 (1.27-3.51) | |
| >60 | 4.40 (2.57-7.51) | 4.18 (2.37-7.37) | |
| Charlson (points) | |||
| 0 | 1.00 | 1.00 | |
| 1 and more | 2.27 (1.49-3.48) | 2.12 (1.31-3.43) | |
*Adjustment variables: age and sex; †AE: Adverse event; ‡Adjustment variables: age, sex, type of hospitalization, reason for hospitalization; §SAPS3: Simplified Acute Physiology Score