Table 3.
Comparison between participants with atherosclerotic vascular disease and without it
| Parameter | KTRs and controls (n = 82)
|
p-value | KTRs (n = 41)
|
p-value | ||
|---|---|---|---|---|---|---|
| AsVD present (n = 26) | ASVD absent (n = 56) | AsVD present (n = 19) | AsVD absent (n = 22) | |||
| Age (years) | 48.0 (41.0–55.0) | 32.5 (27.0–44.0) | < 0.001* | 48.0 (39.0–62.0) | 30.5 (26.0–40.0) | <0.001 |
| WHR | 0.91 (0.86–0.93) | 0.86 (0.83–0.90) | 0.028# | 0.91 (0.88–0.96) | 0.87 (0.84–0.90) | 0.069 |
| BMI (kg/m2) | 26.5 (24.0–31.2) | 27.1 (21.5–30.0) | 0.273* | 26.2 (23.7–28.2) | 25.3 (20.7–28.7) | 0.513 |
| SBP (mmHg) | 139.2 (132.6–145.9) | 140.1 (132.3–147.0) | 0.855# | 138.0 (128.0–147.0) | 141.1 (126.0–151) | 0.794 |
| AIP | 0.03 (-0.03–0.11) | 0.02 (-0.08–0.12) | 0.729* | 0.02 (-0.13–0.20) | 0.01 (-0.15–0.22) | 0.917 |
| Castelli 1 | 4.1 (3.1–4.9) | 3.1 (2.5–4.1) | 0.033* | 3.53 (3.00–4.80) | 3.36 (2.57–4.16) | 0.403 |
| Castelli 2 | 2.5 (1.6–3.2) | 1.8 (1.3–2.6) | 0.048* | 2.09 (1.53–2.73) | 1.67 (1.12–2.55) | 0.158 |
| LCI | 15.4 (10.1–18.9) | 8.7 (4.4–19.6) | 0.013* | 13.38 (9.13–16.54) | 8.65 (4.61–24.32) | 0.308 |
| Non-HDL | 3.4 (2.8–4.0) | 2.9 (2.3–3.5) | 0.019* | 3.31 (2.76–3.77) | 3.03 (2.36–3.76) | 0.381 |
| AI | 3.0 (2.1–3.9) | 2.1 (1.5–3.2) | 0.034* | 2.53 (2.00–3.80) | 2.36 (1.57–3.36) | 0.403 |
| TC (mmol/L) | 4.5 (4.1–5.1) | 4.3 (3.5–4.8) | 0.071* | 4.46 (4.14–4.93) | 4.47 (3.46–5.09) | 0.666 |
| TG (mmol/L) | 1.3 (1.1–2.1) | 1.3 (0.8–1.7) | 0.139* | 1.29 (0.99–1.89) | 1.32 (1.12–1.95) | 0.855 |
| LDL (mmol/L) | 2.7 (2.2–3.3) | 2.6 (2.0–2.9) | 0.087* | 2.65 (2.19–3.24) | 2.49 (1.45–2.73) | 0.205 |
| HDL (mmol/L) | 1.1 (0.9–1.4) | 1.3 (1.1–1.6) | 0.163* | 1.16 (1.01–1.60) | 1.32 (1.09–1.47) | 0.456 |
| Fibrinogen (g/L) | 3.0 (2.6–3.5) | 2.5 (2.2–3.2) | 0.041* | 3.00 (2.70–3.60) | 2.95 (2.50–3.30) | 0.582 |
| Urine-ACR (mg/mmol) | 2.3 (0.8–8.1) | 0.8 (0.3–2.6) | 0.056* | 2.60 (1.40–10.7) | 9.65 (1.20–30.8) | 0.296 |
| eGFR (mL/min/1.73 m2) | 86.5 (54.0–117) | 97.5 (70.5–116.0) | 0.386* | 71.0 (44.0–115.0) | 70.0 (49.0–84.0) | 0.497 |
| LAD (mm) | 37.5 (32.0–40.0) | 32.0 (29.0–35.0) | <0.001# | 38.0 (35.0–41.0) | 34.5 (30.0–36.0) | 0.011 |
| LVMI (g/m2) | 135.1 (118.2–168.2) | 103.9 (81.6–123.5) | <0.001* | 141.2 (128.2–178.0) | 116.2 (100.7–131.8) | <0.001 |
| Dec. time (ms) | 172.5 (155.0–201.0) | 148.0 (129.5–171.0) | <0.001* | 176.0 (158.0–204.0) | 135.5 (120.0–175.0) | 0.003 |
| EF (%) | 73.0 (64.0–79.0) | 68.0 (62.5–74.0) | 0.229* | 76.0 (64.0–80.0) | 69.0 (64.0–79.0) | 0.574 |
Notes:
#
Mean ± SD, Student’s t-test;
*
median (interquartile range), Wilcoxon rank-sum test.
Abbreviations: KTR, kidney transplant recipient; AsVD, atherosclerotic vascular disease; WHR, waist–hip ratios; BMI, body mass index; SBP, systolic blood pressure; AIP, atherogenic index of plasma; LCI, lipoprotein combine index; HDL, high-density lipoprotein; AI, atherogenic index; TC, total cholesterol; TG, triglyceride; LDL, low-density lipoprotein; urine-ACR, urine albumin–creatinine test; eGFR, estimated glomerular filtration rate; LAD, left atrial diameter; LVMI, left ventricular mass index; Dec. time, mitral valve deceleration time; EF, ejection fraction.