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. 2018 Jul 2;7:e36734. doi: 10.7554/eLife.36734

Figure 1. The CRISPR locus and cOA signalling proteins in S. solfataricus.

Figure 1.

The six CRISPR loci (A-F) are shown in black. There are three type I-A systems (grey), a Csm/III D system (dark blue) and Cmr/III B system (light blue). Adaptation genes are shown in green. Numbers shown correspond to Sso gene numbers; non-Cas genes are omitted. Genes encoding CARF family proteins are outlined in purple. The structures of two CARF proteins, Sso1389 (Csx1) and Sso1445 (Csa3), are shown. The SDS-PAGE gels show purified Csx1 (Sso1389) wild-type and variant H345N, and the Csm complex.