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. 2018 Jul 10;7:e35788. doi: 10.7554/eLife.35788

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© 2018, Montefiori et al

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Figure 7. — (A–C) Gene Ontology analysis for target genes looping to (A) cardiac arrhythmia SNPs, (B) myocardial infarction SNPs, and (C) heart failure SNPs. (D) The SORT1 promoter loops to a distal myocardial infarction locus (Musunuru et al., 2010). The rs12740374 SNP shown to disrupt a C/EBP binding site in (Musunuru et al., 2010) is colored red. (E) The ACTA2 promoter loops to the 10q21 heart failure locus (Smith et al., 2010). Zoom plots depict the full interacting region overlapping GWAS LD SNPs. For clarity, only interactions for the indicated gene are shown.