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. Author manuscript; available in PMC: 2018 Nov 16.
Published in final edited form as: Pediatr Res. 2018 May 16;83(5):943–953. doi: 10.1038/pr.2018.33

Table 3.

A Allelic frequencies of rs7820058 in Surgical NEC in infants surviving >7d vs. survival without medical or surgical NEC across the entire NRN cohort.
P<0.0001 Chi square (O.R. 4.72, 2.51 - 8.88) NEC (n=60) NO NEC (n=1092)
Major Allele (A) 45 (75%) 1020 (93.4%)
Minor Allele (G) 15 (25%) 72 (6.6%)
B Allelic frequencies of rs7820058 in Surgical NEC in infants surviving >7d vs. survival without medical or surgical NEC among non-Hispanic Caucasians
P=0.1135 (OR: 3.52, 95% CI 0.67 - 18.4) NEC (n=8) NO NEC (n=266)
Major Allele (A) 6 (75%) 243 (91.3%)
Minor Allele (G) 2 (25%) 23 (8.6%)
C Allelic frequencies of rs7820058 in Surgical NEC in infants surviving >7d vs. survival without medical or surgical NEC among African-Americans
P<0.01 (OR 3.38: 95% CI 1.46-7.83)
Chi square
NEC (n=40) NO NEC (n=566)
Major Allele (A) 32 (80%) 527 (93.1%)
Minor Allele (G) 8 (20%) 39 (6.9%)
D Allelic frequencies of rs7820058 in Surgical NEC in infants surviving >7d vs. survival without medical or surgical NEC among Hispanic Caucasians
P<0.0001 OR (17.86, 95% CI 4.82-66.2) NEC (n=12) NO NEC (n=260)
Major Allele (A) 7 (68.3%) 250 (96.1%)
Minor Allele (G) 5 (41.7%) 10 (3.9 %)