Table 3.
A Allelic frequencies of rs7820058 in Surgical NEC in infants surviving >7d vs. survival without medical or surgical NEC across the entire NRN cohort. | ||
---|---|---|
P<0.0001 Chi square (O.R. 4.72, 2.51 - 8.88) | NEC (n=60) | NO NEC (n=1092) |
Major Allele (A) | 45 (75%) | 1020 (93.4%) |
Minor Allele (G) | 15 (25%) | 72 (6.6%) |
B Allelic frequencies of rs7820058 in Surgical NEC in infants surviving >7d vs. survival without medical or surgical NEC among non-Hispanic Caucasians | ||
---|---|---|
P=0.1135 (OR: 3.52, 95% CI 0.67 - 18.4) | NEC (n=8) | NO NEC (n=266) |
Major Allele (A) | 6 (75%) | 243 (91.3%) |
Minor Allele (G) | 2 (25%) | 23 (8.6%) |
C Allelic frequencies of rs7820058 in Surgical NEC in infants surviving >7d vs. survival without medical or surgical NEC among African-Americans | ||
---|---|---|
P<0.01 (OR 3.38: 95% CI 1.46-7.83) Chi square |
NEC (n=40) | NO NEC (n=566) |
Major Allele (A) | 32 (80%) | 527 (93.1%) |
Minor Allele (G) | 8 (20%) | 39 (6.9%) |
D Allelic frequencies of rs7820058 in Surgical NEC in infants surviving >7d vs. survival without medical or surgical NEC among Hispanic Caucasians | ||
---|---|---|
P<0.0001 OR (17.86, 95% CI 4.82-66.2) | NEC (n=12) | NO NEC (n=260) |
Major Allele (A) | 7 (68.3%) | 250 (96.1%) |
Minor Allele (G) | 5 (41.7%) | 10 (3.9 %) |