Skip to main content
. 2018 Mar 6;32(8):4132–4144. doi: 10.1096/fj.201701090R

Figure 2.

Figure 2

Removal of stratum corneum and topical p(I:C) treatment leads to strong up-regulation of maturation marker CD83 on LCs. A, C) Merged images of epidermal sheets with CD83, CD207 (to visualize LCs), and nuclear [Hoechst (H)] staining 24 and 48 h after removal of stratum corneum and with application of p(I:C) or left untreated and culture. Scale bars, 50 µm. B, D) Bar graphs show percentages of CD83+CD207+ LCs among total CD207+ LCs in untreated (UT) epidermal sheets before culture and at 24 and 48 h for indicated treatments. Values are means ± sem of results from 3 independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001 compared to untreated, cultured group; 1-way ANOVA test. Strp, stripped.