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. Author manuscript; available in PMC: 2019 Jan 4.
Published in final edited form as: Nature. 2018 Jul 4;559(7714):356–362. doi: 10.1038/s41586-018-0288-7

Figure 3. The venous-to-arterial fate change is gradual and culminates in an expression threshold.

Figure 3

(a) Coronary differentiation pathway (dashed arrow). (b–e) Gene expression along the differentiation pathway. Dotted lines, SVc expression levels; red shading, pre-artery cells. (f) Model based on known marker gene patterns. (g) Cell cycle genes decreased in pre-artery cells. CV, coronary vessel; SVc, sinus venosus-coronary progenitors.