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Profiling compound E5 on kinase inhibition.
| Kinase | IC50 (µM)a | Kinase | IC50 (µM)a |
|---|---|---|---|
| PDGFRα | 0.40 | FGFR1 | >25 |
| PDGFRβ | 0.93 | FGFR2 | >25 |
| c-KIT | 0.51 | B-raf | >25 |
| CSF1R | 1.12 | Raf-1 | >25 |
| FLT3 | >25 | EGFR | >25 |
| ABL1 | 9.35 | BLK | >25 |
| ABL2 | 4.36 | LCK | >25 |
aIC50: 50% inhibitory concentration (averages of two separate experiments).
