Figure 3.
Differentially expressed genes in Th17 cell cultures on day 3. Naïve human CD4 T cells were cultured under four conditions for three days (media, Th17-inducing cytokines (Th17 conditions), Th17 + FICZ, Th17 + CH223191), followed by RNA-seq. Left: Venn diagram showing the number of differentially expressed genes for each condition compared to the Th17 group. Overlapping areas of circles represent genes regulated by multiple treatments. Right: Heat map showing relative expression of the genes regulated by all three treatments compared to the media control.