Table 3.

Multivariate analysis of the effect of telomere length and composite genetic risk score on melanoma-specific survival.

	Composite genetic risk score/Telomere length*	N	Dead	HR (95% CI)Ɨ	P
Telomere length	Low risk + long telomeres	208	8	ref
	Low risk + short telomeres	239	24	1.74 (0.78–3.99)	0.17
	High risk + long telomeres	197	17	2.41 (1.04–5.61)	0.04
	High risk + short telomeres	213	27	2.19 (0.97–4.91)	0.06

*The composite genetic risk score was dichotomized at median distribution (low risk ≤ 0 and high risk > 0). The telomere length was dichotomized at median distribution of T/S ratios (long > 1.20 and short ≤ 1.20).

^ƗHazard ratio (HR) was adjusted for age at diagnosis, gender, number of nevi, tumor location and tumor stage.