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. 2018 Jul 19;8:10936. doi: 10.1038/s41598-018-29188-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Enamel surface hardness change (∆%SH; median incl. 25 and 75 percentiles) related to baseline after pellicle modification and after 72 h of biofilm formation and intermitted “cleaning”. NOTE: Negative values represent decrease in SH, positive values represent increase in SH. Statistically significant differences between the modification and the control are shown.