Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jul 19;8:10907. doi: 10.1038/s41598-018-29367-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Density plot of Difference between Densities: the negative intensity (red) shows the locations where a larger fraction of cells scores for patients than for control individuals; positive intensities (blue) contain cells with larger fractions of normal cells. White areas either contain no cells or have similar fractions in both groups of individuals. The axes report the variance explained by the SCA Control Model for the control individuals, on which the DbD is calculated. Loadings of the SCA Control Model are represented as vectors: loadings with similar directions indicate positive co-expression (like for CD16, CRTH2 and CD193, CD4) and with opposite directions indicate negative (like for CD3 and CD16) co-expression of both surface markers. Orthogonal vectors indicate surface markers that express independently, e.g.CD8 and CD123.