Table 3.
Effects of Au-NPs on cardiac marker enzyme measured in normal and ISO-induced hyperthyroid heart disease groups.
| Group | 0 nm | 5 nm | 40 nm | 100 nm | |
|---|---|---|---|---|---|
| AST(U/L) | Ctrl | 261.00 ± 63.61 | 354.8 ± 77.08 | 450.33 ± 153.05 | 301.33 ± 49.70 |
| HHD | 154.75 ± 29.56 | 168.8 ± 27.92 | 157.4 ± 12.93* | 288.33 ± 56.02* | |
| CHO1(mmol/L) | Ctrl | 1.09 ± 0.04 | 1.14 ± 0.10 | 1.09 ± 0.10 | 1.03 ± 0.09 |
| HHD | 1.27 ± 0.21 | 1.10 ± 0.02 | 0.96 ± 0.09 | 0.97 ± 0.06 | |
| TG(mmol/L) | Ctrl | 0.83 ± 0.20 | 0.60 ± 0.09 | 0.7 ± 0.20 | 0.39 ± 0.03 |
| HHD | 1.08 ± 0.14 | 0.67 ± 0.07* | 0.54 ± 0.14* | 0.81 ± 0.06 | |
| HDL-C(mmol/L) | Ctrl | 0.34 ± 0.03 | 0.36 ± 0.03 | 0.4 ± 0.04 | 0.33 ± 0.005 |
| HHD | 0.31 ± 0.005 | 0.4 ± 0.03 | 0.32 ± 0.04 | 0.33 ± 0.03 | |
| LDL-C(mmol/L) | Ctrl | 0.34 ± 0.04 | 0.29 ± 0.04 | 0.27 ± 0.04 | 0.3 ± 0.04 |
| HHD | 0.45 ± 0.07 | 0.3 ± 0.02 | 0.26 ± 0.02* | 0.33 ± 0.05 | |
| APOA(g/L) | Ctrl | 0.00067 ± 0.001 | 0.00025 ± 0.00027 | 0.00125 ± 0.001 | 0.0002 ± 0.00024 |
| HHD | 0.0005 ± 0.0015 | 0.00026 ± 0.00037 | 0.0005 ± 0.001 | 0.00028 ± 0.00028 | |
| APOB(g/L) | Ctrl | 0.0067 ± 0.00033 | 0.0142 ± 0.00217* | 0.017 ± 0.001** | 0.007 ± 0.001 |
| HHD | 0.007 ± 0.002 | 0.007 ± 0.00071 | 0.0065 ± 0.00065 | 0.006 ± 0.001 | |
| LDH(U/L) | Ctrl | 875.33 ± 73.44 | 770.25 ± 94.82 | 412.0 ± 50.0* | 392.0 ± 93.74* |
| HHD | 1504.0 ± 267.0 | 1591.5 ± 365.0 | 904.0 ± 40.1 | 1449.5 ± 9.5 | |
| HBDH(U/L) | Ctrl | 337.33 ± 18.32 | 270.5 ± 27.67 | 185.0 ± 23.0* | 374.0 ± 45.0** |
| HHD | 501.0 ± 122.0 | 540.0 ± 123.37 | 316.25 ± 10.36 | 474.0 ± 39.0 | |
| CK(U/L) | Ctrl | 1061.25 ± 16.38 | 2027.0 ± 62.91* | 911.0 ± 41.85 | 1022.0 ± 16.0 |
| HHD | 748.25 ± 111.57 | 1751.0 ± 316.15* | 780.8 ± 180.83 | 1045.33 ± 145.83 | |
| CKMB(U/L) | Ctrl | 683.0 ± 60.34 | 462.75 ± 41.84* | 324.5 ± 24.5* | 1108.5 ± 88.5 |
| HHD | 955.0 ± 70.0§ | 1191.75 ± 206.77 | 619.75 ± 36.77** | 952.5 ± 3.5 |
*P < 0.05, **P < 0.01, ***P < 0.001; n = 6.