. 2018 Jul 13;9:1590. doi: 10.3389/fimmu.2018.01590

Table 3.

A comparison of absolute serum levels (μg/mL) and proportions of IgG subclasses (%IgG) vs. %B cells in individuals with clinically isolated syndrome (n = 20).

% B cells	Phenotype	Statistic	IgA	IgM	Total IgG	Calculated IgG1	IgG2	IgG3	IgG4	Calculated IgG1% IgG	IgG2% IgG	IgG3%IgG	IgG4% IgG
Transitional B cells	CD19⁺CD20⁺CD27⁻IgD⁺CD24^hiCD38^hi	ρ	−0.25	−0.28	−0.41	−0.40	−0.12	−0.36	0.15	−0.10	0.14	0.04	0.28
Transitional B cells	CD19⁺CD20⁺CD27⁻IgD⁺CD24^hiCD38^hi	p-Value	0.30	0.24	0.08	0.08	0.63	0.12	0.53	0.65	0.56	0.86	0.23

Switched memory B cells	CD19⁺CD20⁺CD27⁺IgD⁻	ρ	−0.25	−0.23	0.10	0.23	−0.34	0.08	−0.17	0.55	−0.47	−0.01	−0.24
Switched memory B cells	CD19⁺CD20⁺CD27⁺IgD⁻	p-Value	0.28	0.33	0.68	0.33	0.14	0.73	0.47	0.01	0.04	0.97	0.31

Non-switched memory B cells	CD19⁺CD20⁺CD27⁺IgD⁺	ρ	−0.23	−0.28	0.06	0.04	−0.03	0.23	−0.01	−0.04	−0.07	0.05	0.03
Non-switched memory B cells	CD19⁺CD20⁺CD27⁺IgD⁺	p-Value	0.33	0.23	0.82	0.86	0.89	0.32	0.96	0.88	0.76	0.85	0.91

CD27 + memory B cells	CD19⁺CD20⁺CD27⁺	ρ	−0.31	−0.41	0.10	0.10	−0.17	0.27	−0.05	0.15	−0.26	0.06	−0.05
CD27 + memory B cells	CD19⁺CD20⁺CD27⁺	p-Value	0.19	0.08	0.68	0.68	0.48	0.25	0.84	0.51	0.27	0.79	0.84

Plasmablasts	CD19⁺CD20⁻CD38^hiCD27^hiIgD⁻CD24⁻	ρ	0.34	0.20	−0.04	0.03	−0.35	0.37	0.10	0.13	−0.28	0.52	0.12
Plasmablasts	CD19⁺CD20⁻CD38^hiCD27^hiIgD⁻CD24⁻	p-Value	0.14	0.15	0.88	0.91	0.13	0.11	0.67	0.59	0.24	0.02	0.62

Double negative memory B cells	CD19⁺CD20⁺IgD⁻CD27⁻	ρ	−0.25	−0.07	−0.15	−0.11	−0.35	0.19	−0.12	0.35	−0.28	0.44	−0.04
Double negative memory B cells	CD19⁺CD20⁺IgD⁻CD27⁻	p-Value	0.30	0.77	0.53	0.64	0.13	0.43	0.63	0.14	0.24	0.06	0.88

Statistically significant correlation is shown in bolded values with shading.

p-Values <0.05 indicates a p-value between 0.01 and 0.05.