Table 1.
Metabolic network model for 13C metabolic flux analysis. For each metabolite carbon atoms are identified using letters to represent successive carbon atoms.
| Glycolysis | |||
|---|---|---|---|
| v1 | Gluc.ext (abcdef) | → | G6P (abcdef) |
| v2 | G6P (abcdef) | ↔ | F6P (abcdef) |
| v3 | F6P (abcdef) | ↔ | FBP (abcdef) |
| v4 | FBP (abcdef) | ↔ | DHAP (cba) + GAP (def) |
| v5 | DHAP (abc) | ↔ | GAP (abc) |
| v6 | GAP (abc) | ↔ | 3PG (abc) |
| v7 | 3PG (abc) | ↔ | PEP (abc) |
| v8 | PEP (abc) | → | Pyr (abc) |
| Pentose Phosphate Pathway | |||
| v9 | G6P (abcdef) | → | Ru5P (bcdef) + CO2 (a) |
| v10 | Ru5P (abcde) | ↔ | X5P (abcde) |
| v11 | Ru5P (abcde) | ↔ | R5P (abcde) |
| v12 | X5P (abcde) | ↔ | EC2 (ab) + GAP (cde) |
| v13 | F6P (abcdef) | ↔ | EC2 (ab) + E4P (cdef) |
| v14 | S7P (abcdefg) | ↔ | EC2 (ab) + R5P (cdefg) |
| v15 | F6P (abcdef) | ↔ | EC3 (abc) + GAP (def) |
| v16 | S7P (abcdefg) | ↔ | EC3 (abc) + E4P (defg) |
| TKTL1 reaction | |||
| v17 | X5P (abcde) | → | AcCoA (ab) + GAP (cde) |